It often arises in the maxilla followed by mandible and affects children and young adults. Central giant cell granulomas cgcg of the jaw are uncommon benign lesions which usually occur in the mandible in young adults. Central giant cell granuloma cgcg is an intraosseous lesion consisting of cellular fibrous tissue that contains multiple foci of hemorrhage, aggregations of multinucleated giant cells and occasionally trabeculae of woven bone. Pdf central giant cell granuloma cgcg, formerly called giant cell reparative granuloma, is a. Central giant cell granuloma cgcg, formerly called giant cell. Pdf central giant cell granuloma of the posterior maxilla. Pdf central giant cell granuloma of the anterior maxilla.
Central giant cell granuloma of the anterior maxilla. Large mandibular central odontogenic fibroma documented. A longterm followup drake mcarthur1, enrique palacios, md, facr, dabr2, and jeremy nguyen, md1 abstract this is a case of a 32yearold female with a. It was jaffe who first introduced the term central giant cell reparative granuloma. Central giant cell granuloma cgcg is an uncommon, benign, proliferative, and nonodontogenic lesion whose etiology is not defined. A central giant cell granuloma in posterior part of maxillaa case. It is an uncommon tumor in jaws, its etiology and pathogenesis is unknown. The central giant cell granuloma is an uncommon, benign and proliferative lesion whose etilogy is not well defined. Central giant cell granuloma is a non neoplastic proliferation of unknown etiology. Central giant cell granuloma cgcg previously called giant cell reparative granuloma is a nonneoplastic proliferative lesion of unidentified etiology. Central giant cell granuloma is a rather rare lesion of the jaws aetiology of which is. Maxillary central giant cell granuloma in a dog johnson.
Central giant cell granuloma is a benign lesion of the jaws which is sometimes aggressive locally. It occurs most commonly in the mandible than in the maxilla. On biopsy, the mass in our case turned out to be a giant cell granuloma, formally called giant cell reparative granuloma, which is a distinct entity from a giant cell tumor and in fact is not considered a. Peripheral giantcell granuloma pgcg is an oral pathologic condition that appears in the mouth as an overgrowth of tissue due to irritation or trauma.
On biopsy, the mass in our case turned out to be a giant cell granuloma, formally called giant cell reparative granuloma, which is a distinct entity from a giant cell tumor and in fact is not. Central giant cell granuloma cgcg is a lesion that appears to be unique to the jaws, 1115 although the socalled giant cell reaction of the hands and feet shares many features. In 1953, jaffe described it as reparative granuloma of jaw bones. This peripheral giant cell granuloma involved the maxillary gingiva associated with an erupting central incisor of a 6yearold girl. The first type is nonaggressive, slow growing, does not show root resorption or cortical perforation, and often shows new bone formation. Central giant cell granuloma cgcg is an intraosseous lesion consisting of. Pdf central giant cell granuloma cgcg formerly called giant cell. The referring doctor had suggested a diagnosis of eruption. Because of its overwhelming incidence on the gingiva, the condition is associated with two other diseases, pyogenic granuloma. Giant cell granuloma is an uncommon bony lesion in the head and neck region, most commonly affecting the maxilla and mandible. Central giant cell granuloma cgcg is an intraosseous lesion consisting of cellular fibrous tissue that contains multiple foci of hemorrhage, aggregations of multinucleated giant cells and occasionally. Central giant cell granuloma cgcg is a benign intraosseous lesion that occurs in long bones. Simultaneous appearance of cofs and odontogenic cysts or giantcell granuloma.
Central giant cell granulomas of the condyle are rare. Case report giant cell granuloma of the maxilla usman haider uzbek, iram mushtaq oral and maxillofacial unit, department of dentistry, ayub medical college, abbottabad. Central giant cell granuloma cgcg, formerly called giant cell reparative granuloma, is a nonneoplastic proliferative lesion of an unknown aetiology. The histological diagnosis was central giant cell granuloma. It accounts for 7% benign maxillary tumors, and females are predominantly. It occurs most commonly in mandible, but can also occur in maxilla. Central giant cell granulomas are benign tumours of the mandible, presenting in children and young adults. Radiological and epidemiological aspects of central giant cell. Treatment included surgical resection of a central giant cell granuloma. Central giant cell granuloma is a nonneoplastic proliferative lesion of unknown etiology. Giant cell central granuloma gccg is an uncommon pseudotumor of the maxilla. The central giant cell granuloma cgcg is an uncommon benign bony lesion that accounts for less than 7% of all benign lesions of the jaws in toothbearing areas. The central giant cell granuloma is an uncommon, benign and proliferative pathological condition accounting for less than 7% of all benign lesions of the jaws whose etiology is not clearly explained.
Central giantcell granuloma cgcg is a localised benign condition of the jaws. We present a case of an aggressive central giant cell granuloma. Who categorize it as a bonerelated lesion, not a tumor, although its clinical behavior and. Central giant cell granuloma cgcg as described by jaffe in 1953 is an idiopathic nonneoplastic proliferative intraosseous lesion consisting of cellular fibrous tissue that contains multiple foci of haemorrhage, aggregations of multinucleated giant cells and occasionally trabeculae of woven bone. Maxillary central giant cell granuloma in a dog, journal. The case described here involved maxilla which was treated with surgical excision. Read maxillary central giant cell granuloma in a dog, journal of small animal practice on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available. This group of lesions includes central giant cell granuloma. The most common treatment is curettage,which has a high recurrence rate, particularly in more. Giant cell granuloma an overview sciencedirect topics. Most mandibular lesions occur anterior to first molars. Central giant cell granuloma cgcg was an uncommon lesion that is.
We present two cases of central giant cell granuloma in the temporal bone. Although it is a benign disease process, it can also be locally destructive. Central giant cell granuloma cgcg as described by jaffe in 1953 is an idiopathic nonneoplastic proliferative intraosseous lesion consisting of cellular fibrous tissue that contains multiple foci of. An aggressive central giant cell granuloma in a pediatric. Pdf central giant cell granuloma of the temporal bone. Many maxillary lesions present similar histological patterns, especially in the presence of giant cells. Pdf central giant cell granuloma of mandible mohit.
In our report, we share with you a rare case of maxillary aggressive central. Coordinated pediatric reconstruction and rehabilitation of. Central giant cell granuloma cgcg, formerly called giant cell reparative granuloma, is a nonneoplastic proliferative lesion of unknown etiology. An aggressive central giant cell granuloma treated successfully by. Aggressive central giant cell granuloma of the maxilla. Treatment included surgical resection of a central giant cell granuloma and obturation with a removable interim prosthesis. It occurs most commonly on the mandible than in maxilla. The purpose of this study was to determine the ct characteristics and describe possible mr imaging features of gcg. A central giant cell granuloma in posterior part of. Surgery is the traditional and still the most accepted treatment for giant cell granuloma. It is twice as common in females and is more likely to occur before age 30. It accounts for 7% benign maxillary tumors, and females are predominantly affected in 23ofcases before age 20years 1. Central giant cell granuloma of the mandibular condyle. Central giant cell granuloma cgcg is an intraosseous lesion consisting of fibrous cellular tissue that contains multiple foci of hemorrhage, multinucleated giant cells, and occasional trabeculae of woven.
Ct showed an enhancing tumor causing a smoothly margined temporal squamosa and floor of the middle fossa. Central giant cell granuloma of the mandible american. A retrospective analysis was conducted of patients with central giant cell granuloma of the mandible who were treated between 1991 and 2000, in the oral and maxillofacial surgery unit at jordan. An unusual presentation of a maxillary central giant cell granuloma. Central giantcell is a benign lesion that predominantly involves the bone of the mandible and maxilla with a wide varia. Large generalized radiopacity occupying right maxillary sinus.
Clinically and radiologically, a differentiation between aggressive and nonaggressive lesions can be made. Giant cell reparative granuloma accounts for 17% of all benign lesions of the jaw. Giant cell granuloma is an uncommon bony lesion in the head and neck. Coordinated pediatric reconstruction and rehabilitation of maxillary. Peripheral giant cell granuloma central giant cell granuloma. Central giant cell granuloma of the posterior maxilla. Central giant cell granuloma in anterior maxilla shwetang goswami1, haripriya2, yashwanth yadav3, ram mohan4 abstract. Divided into non and aggressive subtypes, the aggressive subtype is relatively rare and can occasionally progress rapidly, resulting in significant morbidity. Giant cell granuloma gcg is an uncommon, benign, proliferative, intraosseous lesion representing granuloma central if intraosseous. Cgcg accounts for less than 7 % of all benign lesions of mandible and maxilla. A young labrador dog had a rapidly enlarging osteolytic lesion of the left maxillary bone. Large mandibular central odontogenic fibroma documented over 20 years. Cgcg was formerly regarded as a reparative process and was, accordingly, called central giant cell reparative granuloma. Central giant cell granuloma cgcg is a benign lesion of the jaws with an unknown etiology.
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